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Tuesday, June 12, 2012
Busted Freezer Melts 150 Brains [Science]
amsecproject: RT @NaturalEnergyHQ: RT @amsecproject: Prudence Needed in Department of Commerce Tariff Decision @grotec12 #energy #solar #trade #com... ...
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Recruiting Experienced Basketball Gamers | Backlinkarticles
The National Basketball Association relies on many individuals to recruit the players which are in the end chosen to perform skilled basketball. These experts have degrees that go over quite a few places of the activity, and many have expertise with all the video game of basketball on a private level. Some of those professionals basically have a watch for recognizing talent inside the oddest areas, but still feel confident within their abilities to recruit the ideal immediately after only seeing them perform basketball once or two times.
A few of these professionals utilized to invest lots of hours driving from one farm to a further seeking players who confirmed specialist talent that experienced yet to become created to play the sport on a professional level. The scouting positions they held for so many many years, required them to find out the lingo employed in scouting lengthy just before text messaging lingo appeared.
These pros of basketball were generally able to talk about all of the opportunities of taking part in specialist basketball directly having an individual ahead of the participant knew sufficient concerning the recreation to negotiate contracts or go over which team they wanted to perform for. Finding fresh talent is an exciting thing and getting the first one to go over taking part in expert basketball with a new expertise can also be considered an energizing encounter. Obtaining talent for skilled basketball calls for people today which have a correct sensation of what?s expected to play the sport.
At times, it will take a professional basketball player to locate expertise which is ideal fitted to the sport. Basketball calls for greater than the potential to sink a basketball into an internet from twenty toes absent. It demands an individual that may be prepared to coach challenging and become a part of the group idea that could just get them to some championship playoff one day. Some of the experts involved with basketball have already been around the sport for that far better portion of their daily life controlling a basketball group in the school level.
A few of the head coaches in specialist basketball were when university basketball gamers and felt they could make their mark inside the activity by turning expert and working for that National Basketball Affiliation in an advisory position. A few of these pros are great with studies and serve the Affiliation by determining which unskilled players have the right mixture of talents to create a productive career from playing basketball for a living. They get that information on a particular participant and make their recommendations towards the owners from the group.
Some experienced focus on methods and are able to work out which sport plans operate best for which groups. Some of these pros in basketball have worked powering the scenes for numerous years for many NBA teams and know just how items are completed and what issues they became conscious of that must be changed. You?ll find adjustments occurring all over the National Basketball Affiliation and also the NBA is counting on these pros to manual the game in the ideal direction. Recruiting specialist basketball players demands team help from folks that certainly have the energy to produce alterations happen.
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Fighting cancer with the immune system
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Public release date: 11-Jun-2012[ | E-mail |
Share ] Contact: Sarah Jackson
press_releases@the-jci.org
Journal of Clinical Investigation
The human immune system has a natural ability to identify and attack tumor cells. Natural killer (NK) cells are innate immune cells that are particularly effective at killing tumor cells due to their ability to secrete cytotoxic enzymes. However, mutations have allowed many types of tumors to develop a resistance to NK-mediated killing through ill-defined mechanisms. Dr. Jerome Ritz and colleagues at the Dana-Farber Cancer Institute in Boston sought to pinpoint some of these mechanisms using a library of short hairpin RNAs (shRNA), a type of RNA that binds complementary RNA sequences in the cell and prevents their transcription into proteins.
His group used a multiple myeloma cell line to screen for genes whose reduced expression increased susceptibility of the cancer cells to NK-mediated death. They identified dozens of genes that, when shut down by shRNA, allowed increased tumor cell killing by NK cells. The strongest effect was induced by silencing proteins called JAK1 and JAK2, kinases important for integrating signals from many membrane receptor proteins. In addition to targeting these kinases by shRNA, the research team showed that pharmacological inhibition of JAK1 and 2 also increased tumor cell killing. Many kinase inhibitors being used or tested today target genes identified in this screen. The researchers suggest that targeting the JAK1 and 2 pathways in particular may aid in eradicating tumors that have developed mechanisms to escape NK cell killing.
###
TITLE:
Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells
AUTHOR CONTACT:
Jerome Ritz
Dana Farber Cancer Institute, Boston, MA, USA
Phone: 617/632-3465; Fax: 617-632-5167; E-mail: jerome_ritz@dfci.harvard.edu
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 11-Jun-2012[ | E-mail |
Share ] Contact: Sarah Jackson
press_releases@the-jci.org
Journal of Clinical Investigation
The human immune system has a natural ability to identify and attack tumor cells. Natural killer (NK) cells are innate immune cells that are particularly effective at killing tumor cells due to their ability to secrete cytotoxic enzymes. However, mutations have allowed many types of tumors to develop a resistance to NK-mediated killing through ill-defined mechanisms. Dr. Jerome Ritz and colleagues at the Dana-Farber Cancer Institute in Boston sought to pinpoint some of these mechanisms using a library of short hairpin RNAs (shRNA), a type of RNA that binds complementary RNA sequences in the cell and prevents their transcription into proteins.
His group used a multiple myeloma cell line to screen for genes whose reduced expression increased susceptibility of the cancer cells to NK-mediated death. They identified dozens of genes that, when shut down by shRNA, allowed increased tumor cell killing by NK cells. The strongest effect was induced by silencing proteins called JAK1 and JAK2, kinases important for integrating signals from many membrane receptor proteins. In addition to targeting these kinases by shRNA, the research team showed that pharmacological inhibition of JAK1 and 2 also increased tumor cell killing. Many kinase inhibitors being used or tested today target genes identified in this screen. The researchers suggest that targeting the JAK1 and 2 pathways in particular may aid in eradicating tumors that have developed mechanisms to escape NK cell killing.
###
TITLE:
Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells
AUTHOR CONTACT:
Jerome Ritz
Dana Farber Cancer Institute, Boston, MA, USA
Phone: 617/632-3465; Fax: 617-632-5167; E-mail: jerome_ritz@dfci.harvard.edu
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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Monday, June 11, 2012
CellScope Nabs $1M From Khosla Ventures To Turn Your Smartphone Into A Microscope
Founded in the mobile microscopy lab at UC Berkeley, a young startup called CellScope is on a mission to turn your smart, mobile devices into a microscope, giving parents the ability to perform easy, at-home diagnoses. The startup has been developing its first product for over a year now, adding functionality that will give consumers the ability to share images of the eardrum with remote pediatricians for diagnosis, treatment, and monitoring. To help bring its device to shelves near you, CellScope is today announcing that it has raised $1 million in seed funding from Khosla Ventures.carrie underwood jessica simpson ryan seacrest kentucky derby beltane ryan o neal dark knight rises trailer
India's $500-b export target set to face protectionist hurdle
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Shugo Chara 1x1 Search
Okay, so I'm sure by the title you already have some sort of idea of what I'm looking for.
I've always been a fan of Shugo Chara - it's a cute story with adorable characters and romances.
The problem that I see is that Shugo Chara roleplays only last a couple of posts/pages because its hard with so many people.
SO. THIS is my proposition.
I want to do a 1x1 featuring the Joker and the Easter Pawn.
(in the actual story, these characters would be Amu and Ikuto)
Their relationship is always very interesting no matter the roleplayers, so I wanted to do this just to see how it works out.
What I'm looking for in a partner:
-you can be male or female, but you will be playing the male Easter Pawn
-dedication is a real important aspect
-comfortable with romance
-literacy! someone who has good grammar, spelling, and writes generally around 400-600 words per response
-flexible with changes in the plot
-has previous knowledge on Shugo Chara (manga/anime)
-will help make a more interesting plot line
-knows how to have fun
What I'm looking for in the character:
-male
-a pawn of Easter, but strives for freedom
-flirtatious and/or seductive (think Ikuto's personality)
-likes to have fun but can be serious
-outwardly self-centered, inwardly selfless
-has an important reason for hunting the embrio
-1 or 2 charas
-good sense of humor
I'd prefer to do this via PM just because it is easier, but if you'd rather the roleplay tab I don't mind.
Just to make things clear, the Joker will be in highschool, not elementary. Ikuto can be an upperclassman or can have recently graduated.
(this doesn't mean I want a pedo character... if he has graduated, he would have JUST graduated)
Interested? Send me a reply either in this topic or by PM!
Thanks(;
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